This test evaluates blood for the immune response to Candida albicans. This is the least sensitive of all of the tests offered.
The Anti-Candida Antibody Panel is an analysis of serum (blood) Candida antigen, in addition to IgG, IgA, and IgM antibodies specific for Candida. The antigen is Candida and the antibody is produced by white blood cells in response to candida.
IgM is the first antibody formed after primary exposure to antigen, and reflects a present infection. IgM readily activates complement, and assists the phagocytic system to eliminate antigen from the intravascular space.
IgG is the predominant antibody formed from secondary exposure to antigen, and reflects a past or ongoing infection. It is also the largest class of antibodies present in the body. It is produced as IgM antibody levels decrease after primary exposure. IgG activates complement, and assists the phagocytic system to eliminate antigen from the extravascular space.
IgA is found in mucous secretions and is important in local (mucosal) immunity. Elevated IgA antibodies may reflect a fungal infection that is affecting mucus membranes throughout the body. It is sometimes associated with a more superficial Candida infection. Mucus is commonly found throughout the length of the digestive tract, as well as in the oral cavity, sinuses, lungs, and vaginal tissues.
An antibody test is a good test to do in conjunction with a stool test.