CBS/BHMT Assist is a combination product that supports healthy digestion, as well as the methionine pathway. The BHMT variant inhibits the conversion of homocysteine into methionine through what is called the middle pathway. The CBS variant upregulates the pathway, potentially causing homocysteine to rush down the trans-sulfuration pathway up to 10 times faster than normal. Even without the BHMT variant, supporting the pathway to make it more efficient is useful when someone has the CBS variant.