Progesterone Pure is a hypoallergenic formula free of chemicals found in cosmetic skin creams, particularly synthetic fragrances and preservatives that can be agents for triggering skin sensitivities and allergies. Karuna Progesterone Pure is free of alcohol, parabens and urea. Each 2 oz. tube is standardized, quality controlled and safety-sealed to prevent oxidation and bacterial contamination. Each 2 oz. tube contains natural progesterone USP (25 mg per ¼ tsp.), which applies easily and absorbs rapidly into the skin, leaving no sticky or oily residue.